Human astrocytoma U138MG cells express predominantly type-A endothelin receptor

Developmental changes in Endothelin-1 and Endothelin type A receptor expression in the lungs of chickens (Broiler versus layer)

Background: Broilers lung mechanisms that regulate endothelin (ET) in the lung are complex and poorly understood. Objectives: Methods: In this experiment lung ET-1 mRNA levels and lung mRNA expression for the ET(A) receptors were determined in lung tissue weekly (term = 42 days, intervals = 7 days). Serum endothelin concentration was also measured at these ages. Results: The study showed that e...

Human Trophoblast Progenitor Cells Express and Release Angiogenic Factors

Trophoblast stem cells develop from polar trophoectoderm and give rise to the cells that generate the placenta. Trophoblast cells are responsible for the uterinal invasion and vascular remodeling during the implantation of the embryo. However this knowledge is not yet to be confirmed for trophoblast progenitor cells (TPCs). In this study, we aimed to demonstrate that human TPCs (hTPCs) express ...

Human intestinal epithelial cells express a novel receptor for IgA.

Binding and transport of polymeric Igs (pIgA and IgM) across epithelia is mediated by the polymeric Ig receptor (pIgR), which is expressed on the basolateral surface of secretory epithelial cells. Although an Fc receptor for IgA (FcalphaR) has been identified on myeloid cells and some cultured mesangial cells, the expression of an FcalphaR on epithelial cells has not been described. In this stu...

Human T Cells Express the C 5 a Receptor

Endothelin Type a Receptor Mediates Endothelin-1-induced Upregulation of Nadph Oxidase Activity in Human Aortic Smooth Muscle Cells

Endothelin system plays an important role in the pathophysiology of cardiovascular diseases. Endothelin-1 (ET-1), the main effector of the system, regulates important physiological processes including vascular tonus, cellular growth and proliferation. In pathological conditions such as diabetes, hypertension, obesity and atherosclerosis, excessive ET-1 synthesis induces oxidative stress, inflam...